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Article

Mitochondria damage checkpoint, aging, and cancer.

Annals of the New York Academy of Sciences - 1 May 2006

Singh Keshav K

Abstract excerpt

There is growing evidence supporting the progressing decline in mitochondrial function with age. Mitochondria are the major site of reactive oxygen species (ROS) production in the cell; therefore it is likely that progressive decline in mitochondrial function is due to the accumulation of oxidative damage with age. Despite this notion, a role for mitochondria in cellular senescence has been largely ignored. Our...

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PMID: 16803984
DOI: 10.1196/annals.1354.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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