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Article

Mitochondrial Dysfunction Meets Senescence.

Trends in biochemical sciences - 1 Mar 2016

Gallage Suchira, Gil Jesús

Abstract excerpt

Cellular senescence and mitochondrial dysfunction are hallmarks of ageing, but until now their relationship has not been clear. Recent work by Wiley et al. shows that mitochondrial defects can cause a distinct senescence phenotype termed MiDAS (mitochondrial dysfunction-associated senescence). MiDAS has a specific secretome that is able to drive some of the aging phenotypes. These findings suggest novel...

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PMID: 26874922
DOI: 10.1016/j.tibs.2016.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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