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Mitochondrial Dysfunction and Cell Senescence: Cause or Consequence?

1 Mar 2006

Abstract excerpt

The mitochondrial theory of aging remains to date one of the most popular theories of aging. One major model of aging is replicative senescence, where the irreversible loss of division potential of somatic cells occurs after a more or less constant number of cell divisions. Few data are available concerning the role of mitochondria in this model. Here, we review evidence supporting the involvement of mitochondria...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 16608398
DOI: 10.1089/rej.2006.9.64

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