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Article

The mitochondrial genome in aging and senescence.

Ageing research reviews - 1 Nov 2014

Lauri Andrea, Pompilio Giulio, Capogrossi Maurizio C

Abstract excerpt

Aging is characterized by a progressive decline in organism functions due to the impairment of all organs. The deterioration of both proliferative tissues in liver, skin and the vascular system, as well as of largely post-mitotic organs, such as the heart and brain could be attributed at least in part to cell senescence. In this review we examine the role of mitochondrial dysfunction and mtDNA mutations in cell...

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PMID: 25042573
DOI: 10.1016/j.arr.2014.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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