Ankyrins and human disease: what the electrophysiologist should know.

Abstract excerpt

The coordinate activity of ion channels and transporters in cardiac muscle is critical for normal excitation-contraction coupling and cardiac rhythm. In the past decade, human gene variants, which alter ion channel biophysical properties, have been linked with fatal cardiac arrhythmias. Ankyrins are a family of "adaptor" proteins, which play critical roles in the proper expression and membrane localization of ion...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ankyrins
• Share to Arrhythmias, Cardiac
• Share to Electrophysiology