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Article

Association between a functional COMT polymorphism, mental retardation and cognition in Qinba area children.

Yi chuan xue bao = Acta genetica Sinica - 1 Jun 2006

Zhang Ke-Jin, Gao Xiao-Cai, Li Rui-Lin, Chen Chao, Zheng Zi-Jian, Huang Shao-Ping, Zhang Fu-Chang

Abstract excerpt

Catechol-O-methyl transferase (COMT) plays an important role in the metabolism of neurotransmitters. Two alleles of the COMT gene as a result of a G/A transition in the exon 4 can lead to different COMT enzymatic activities. Much genetic research has revealed that this COMT functional polymorphism was related to human psychiatric disorders. Polymerase chain reaction (PCR) and restriction fragment length...

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Source

Identifiers

PMID: 16800379
DOI: 10.1016/S0379-4172(06)60077-2

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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