Article
No association between catechol-O-methyltransferase (COMT) genotype and attention deficit hyperactivity disorder (ADHD) in Japanese children.
Brain & development - 1 Aug 2014
Yatsuga Chiho, Toyohisa Daiki, Fujisawa Takashi X, Nishitani Shota, Shinohara Kazuyuki, Matsuura Naomi, Ikeda Shinobu, Muramatsu Masaaki, Hamada Akinobu, Tomoda Akemi
Abstract excerpt
OBJECTIVE: This study ascertained the association between attention deficit/hyperactivity disorder (ADHD) in Japanese children and a polymorphism of catechol-O-methyltransferase (COMT), a dopamine-control gene. The secondary aim of the study was the evaluation of a putative association between methylphenidate (MPH) effect/adverse effects and the COMT genotype. METHODS: To ascertain the distribution of the...
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