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Article

Genetic distribution and association analysis of DRD2 gene polymorphisms with major depressive disorder in the Chinese Han population.

International journal of clinical and experimental pathology - 1 Jan 2013

He Mei, Yan Hong, Duan Zhao-Xia, Qu Wei, Gong Hai-Yan, Fan Zheng-Li, Kang Jian-Yi, Li Bing-Cang, Wang Jian-Min

Abstract excerpt

Dopamine D2 receptor is involved in reward-mediating mesocorticolimbic pathways. It plays an important role in major depressive disorder (MDD). Three gene polymorphisms Taq1A, C957T and -141C ins/del, were identified in the DRD2 gene among the Western population. These variants in the DRD2 gene might be associated with the susceptibility of MDD patients through affecting the bioeffects of endogenous dopamine...

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Identifiers

PMID: 23696934
PMCID: PMC3657369

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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