Article
The 3' region of the DRD2 gene is involved in genetic susceptibility to schizophrenia.
Schizophrenia research - 1 Mar 2004
Dubertret Caroline, Gouya Laurent, Hanoun Naima, Deybach Jean-Charles, Adès Jean, Hamon Michel, Gorwood Philip
Abstract excerpt
The gene coding for the D2 dopamine receptor (DRD2) is considered as one of the most relevant candidate genes in schizophrenia. Previous genetic studies focusing on this gene yielded conflicting results, for example because of differences in methodology (linkage versus association studies) and variability in the loci analyzed (the DRD2 gene having many polymorphic sites). We used a progressive strategy with two...
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