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Article

Levels of alpha-synuclein mRNA in sporadic Parkinson disease patients.

Movement disorders : official journal of the Movement Disorder Society - 1 Oct 2006

Chiba-Falek Ornit, Lopez Grisel J, Nussbaum Robert L

Abstract excerpt

Lewy bodies, the pathological hallmark of Parkinson's disease (PD), consist largely of alpha-synuclein, a 14.5-kDa presynaptic neuronal protein implicated in familial PD. An increased copy number and elevated expression of wild-type alpha-synuclein (SNCA) has been shown to cause early-onset familial PD. However, it is not clear whether increased alpha-synuclein expression also plays a role in the pathogenesis of...

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Source

Identifiers

PMID: 16795004
DOI: 10.1002/mds.21007

Genes

SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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