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Article

?-Synuclein expression in substantia nigra and cortex in Parkinson's disease

1 May 1999

Abstract excerpt

Mutations in the human alpha-synuclein gene have been identified in several families of European descent with early-onset Parkinson's disease (PD). We sequenced the complete alpha-synuclein cDNA from substantia nigra and cortex from nine patients with PD and eight control subjects. No mutations were found. We then analyzed alpha-synuclein mRNA levels using a ribonuclease protection assay. Two major protected...

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Identifiers

PMID: 10348463
DOI: 10.1002/1531-8257(199905)14:3<417::aid-mds1005>3.0.co;2-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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