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Article

Alpha‐synuclein mRNA expression in oligodendrocytes in MSA

3 Mar 2014

Abstract excerpt

Multiple system atrophy (MSA) is a progressive neurodegenerative disease presenting clinically with parkinsonian, cerebellar, and autonomic features. α-Synuclein (αsyn), encoded by the gene SNCA, is the main constituent of glial cytoplasmic inclusion (GCI) found in oligodendrocytes in MSA, but the methods of its accumulation have not been established. The aim of this study is to investigate alterations in...

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PMID: 24590631
DOI: 10.1002/glia.22653

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