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Altered α‐synuclein, parkin, and synphilin isoform levels in multiple system atrophy brains

14 Oct 2015

Abstract excerpt

Together with Parkinson's disease (PD) and dementia with Lewy bodies, multiple system atrophy (MSA) is a member of a diverse group of neurodegenerative disorders termed α-synucleinopathies. Previously, it has been shown that α-synuclein, parkin, and synphilin-1 display disease-specific transcription patterns in frontal cortex in PD, dementia with Lewy bodies, and MSA, and thus may mediate the development of...

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PMID: 26465922
DOI: 10.1111/jnc.13392

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