Article
The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast.
Molecular biology of the cell - 1 Sept 2006
Kondo-Okamoto Noriko, Ohkuni Kentaro, Kitagawa Katsumi, McCaffery J Michael, Shaw Janet M, Okamoto Koji
Abstract excerpt
Although it is clear that mitochondrial morphogenesis is a complex process involving multiple proteins in eukaryotic cells, little is known about regulatory molecules that modulate mitochondrial network formation. Here, we report the identification of a new yeast mitochondrial morphology gene called MFB1 (YDR219C). MFB1 encodes an F-box protein family member, many of which function in Skp1-Cdc53/Cullin-F-box...
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