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Article

The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance.

The Journal of cell biology - 22 Feb 1999

Shepard K A, Yaffe M P

Abstract excerpt

The mdm17 mutation causes temperature-dependent defects in mitochondrial inheritance, mitochondrial morphology, and the maintenance of mitochondrial DNA in the yeast Saccharomyces cerevisiae. Defects in mitochondrial transmission to daughter buds and changes in mitochondrial morphology were apparent within 30 min after shifting cells to 37 degrees C, while loss of the mitochondrial genome occurred after 4-24 h at...

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Identifiers

PMID: 10037792
DOI: 10.1083/jcb.144.4.711
PMCID: PMC2132935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance.PMID 10037792Read ↗

Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin.Semantic proximity Read ↗

Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability.Semantic proximity Read ↗

The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria.Semantic proximity Read ↗

A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery.Semantic proximity Read ↗

Regulation of mitochondrial morphology and inheritance by Mdm10p, a protein of the mitochondrial outer membrane.Semantic proximity Read ↗

Mimicking human Drp1 disease-causing mutations in yeast Dnm1 reveals altered mitochondrial dynamics.Semantic proximity Read ↗

MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria.Semantic proximity Read ↗

Mdm12p, a component required for mitochondrial inheritance that is conserved between budding and fission yeast.Semantic proximity Read ↗

Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane.Semantic proximity Read ↗

Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast.Semantic proximity Read ↗

The dynamin-like protein DLP1 is essential for normal distribution and morphology of the endoplasmic reticulum and mitochondria in mammalian cells.Semantic proximity Read ↗

Mutational analysis of Mdm1p function in nuclear and mitochondrial inheritance.Semantic proximity Read ↗

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