Article
Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence.
Development (Cambridge, England) - 1 Aug 2006
Kellerer Susanne, Schreiner Silke, Stolt C Claus, Scholz Stefanie, Bösl Michael R, Wegner Michael
Abstract excerpt
Sox8 and Sox10 are two closely related transcription factors of the Sox protein family with overlapping expression patterns during development. They are believed to perform very similar functions because several developmental processes, including enteric nervous system development and oligodendrocyte differentiation, are regulated by both Sox proteins. To analyze the extent of functional equivalence between the...
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