Article
The short consensus repeats 1 and 2, not the cytoplasmic domain, of human CD46 are crucial for infection of subgroup B adenovirus serotype 35.
Journal of controlled release : official journal of the Controlled Release Society - 20 Jul 2006
Sakurai Fuminori, Murakami Sayaka, Kawabata Kenji, Okada Naoki, Yamamoto Akira, Seya Tsukasa, Hayakawa Takao, Mizuguchi Hiroyuki
Abstract excerpt
Human CD46 (membrane cofactor protein) has recently been identified to be an attachment receptor for subgroup B adenoviruses (Ads); however, the precise interaction between human CD46 and subgroup B Ads are just beginning to be understood. In this study, to characterize the interaction between human CD46 and subgroup B Ads, varieties of mutant CD46 were tested for their ability to act as a receptor for Ad...
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