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Localization of Regions in CD46 That Interact with Adenovirus

26 May 2005

Abstract excerpt

A variety of pathogens use CD46, a ubiquitously expressed membrane protein that regulates complement activation, as a cellular attachment receptor. While the CD46 binding sites of several pathogens, including measles virus, Neisseria gonorrhea, and human herpesvirus 6, have been described, the region of CD46 responsible for adenovirus binding has not been determined. In this study, we used competition experiments...

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PMID: 15919905
DOI: 10.1128/jvi.79.12.7503-7513.2005

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