Article
Measles virus receptor properties are shared by several CD46 isoforms differing in extracellular regions and cytoplasmic tails.
The Journal of general virology - 1 Sept 1994
Gerlier D, Loveland B, Varior-Krishnan G, Thorley B, McKenzie I F, Rabourdin-Combe C
Abstract excerpt
Human CD46, a member of the family of regulators of complement activation, has been shown recently to act as a measles virus (MV) receptor, interacting with the virus envelope glycoprotein haemagglutinin (HA). Owing to alternative RNA splicing, several CD46 isoforms are co-expressed in all tissue...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, CD
- CHO Cells
- Cell Membrane
- Cricetinae
- Flow Cytometry
- Genetic Variation
- Humans
- Measles virus
- Membrane Cofactor Protein
- Membrane Glycoproteins
- Transfection
- Virus Replication