Article
In vivo direct molecular imaging of early tumorigenesis and malignant progression induced by transgenic expression of GFP-Met.
Neoplasia (New York, N.Y.) - 1 May 2006
Moshitch-Moshkovitz Sharon, Tsarfaty Galia, Kaufman Dafna W, Stein Gideon Y, Shichrur Keren, Solomon Eddy, Sigler Robert H, Resau James H, Vande Woude George F, Tsarfaty Ilan
Abstract excerpt
The tyrosine kinase receptor Met and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), play an important role in normal developmental processes, as well as in tumorigenicity and metastasis. We constructed a green fluorescent protein (GFP) Met chimeric molecule that functions similarly...
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