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Watching cancer begin: emerging tools to visualize the first steps of tumorigenesis.

Trends in cancer - 1 Jul 2026

Messal Hendrik A, Mourao Larissa, Dörner Lea, Scheele Colinda L G J, van Rheenen Jacco

Abstract excerpt

Understanding tumor initiation is crucial for early interception and prevention. Tumors arise from genetic alterations and microenvironmental changes that together create a niche for malignant growth. Previously, the spatiotemporal dynamics of tumorigenesis were difficult to study. Recent advances in high-resolution intravital microscopy, tissue clearing, and spatial molecular profiling enable direct...

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PMID: 41881769
DOI: 10.1016/j.trecan.2026.02.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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