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PLASQ: a generalized linear model-based procedure to determine allelic dosage in cancer cells from SNP array data.

Biostatistics (Oxford, England) - 1 Apr 2007

Laframboise Thomas, Harrington David, Weir Barbara A

Abstract excerpt

Human cancer is largely driven by the acquisition of mutations. One class of such mutations is copy number polymorphisms, comprised of deviations from the normal diploid two copies of each autosomal chromosome per cell. We describe a probe-level allele-specific quantitation (PLASQ) procedure to d...

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PMID: 16787995
DOI: 10.1093/biostatistics/kxl012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16787995-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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