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Are CYP17 genotypes a biomarker for ovarian cancer in patients with cancer history in their family?

Oncology research - 1 Jan 2006

Yazici Hulya, Tigli Hulya, Kadehci Zuleyha, Kucucuk Seden, Saip Pinar, Issever Halim, Ozcelik Hilmi, Dalay Nejat

Abstract excerpt

BRCA1 and BRCA2 genes are responsible for 5-10% of breast and ovarian cancer cases. However, the vast majority of ovarian and breast cancer cases do not display the hereditary form of the disease. Estrogen-metabolizing genes may also contribute to the predisposition of breast or ovarian cancer. Polymorphic variants of the estrogen-metabolizing gene, CYP17, have been associated with the risk of hormone-related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16783967
DOI: 10.3727/000000006783981279

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Are CYP17 genotypes a biomarker for ovarian cancer in patients with cancer history in their family?PMID 16783967Read ↗

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