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Article

CYP17 promoter polymorphism and breast cancer risk in males and females in relation to BRCA2 status.

British journal of cancer - 24 Mar 2003

Gudmundsdottir K, Thorlacius S, Jonasson J G, Sigfusson B F, Tryggvadottir L, Eyfjord J E

Abstract excerpt

A T-C polymorphism in the promoter region of the CYP17 gene has been associated with male and female breast cancer risk as well as early-onset familial breast cancer. The potential role of this polymorphism was investigated in relation to breast cancer risk in Icelandic male and female carriers and noncarriers of a BRCA2 mutation. The study population consisted of 39 male and 523 female breast cancer cases and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms, Male

Share to Genes, BRCA2

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Share to Promoter Regions, Genetic

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Share to Steroid 17-alpha-Hydroxylase

Source

Open in PubMed Open full text

Identifiers

PMID: 12644832
DOI: 10.1038/sj.bjc.6600839
PMCID: PMC2377070

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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