Article
CYP17 gene polymorphism and its association with high-risk north Indian breast cancer patients.
Journal of human genetics - 1 Jan 2007
Chakraborty Anurupa, Murthy N S, Chintamani Chintamani, Bhatnagar D, Mohil R S, Sharma P C, Saxena Sunita
Abstract excerpt
A single T > C change at the 5' promoter region of the CYP17 gene is reported to be associated with increased risk of breast cancer. This study evaluates the influence of genetic polymorphism of CYP17 on breast cancer susceptibility. Two hundred and forty-two patients with histopathologically confirmed breast cancer and 212 age-matched controls were included in the present study. Information relating to age at...
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