Article
Better identification of patients who benefit from implantable cardioverter defibrillators by genotyping the G protein beta3 subunit (GNB3) C825T polymorphism.
Basic research in cardiology - 1 Sept 2006
Wieneke Heinrich, Naber Christoph N, Piaszek Leon, Sack Stefan, Frey Ulrich H, Heusch Gerd, Erbel Raimund, Siffert Winfried
Abstract excerpt
AIMS: There is a need for better identification of patients at high risk for malignant arrhythmias who would benefit from implantable cardioverter defibrillators (ICD). The purpose of this study was to assess whether the C825T polymorphism in the G-protein beta3 subunit gene, GNB3, might serve as a genetic marker for recurrent ventricular arrhythmias. METHODS AND RESULTS: Genotyping was performed in 82 patients...
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