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Article

Interaction of the ACE D allele and the GNB3 825T allele in myocardial infarction.

Hypertension (Dallas, Tex. : 1979) - 1 Dec 2000

Naber C K, Hüsing J, Wolfhard U, Erbel R, Siffert W

Abstract excerpt

In polygenetic disorders, such as ischemic heart disease, the investigation of gene-gene interactions rather than determination of single gene effects is crucial to better understand the contribution of genetic factors. The 825T allele of the G-protein ss(3)-subunit gene (GNB3) associated with enhanced G-protein signaling is a candidate to interact with the angiotensin-converting enzyme (ACE) deletion/insertion...

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Source

Identifiers

PMID: 11116112
DOI: 10.1161/01.hyp.36.6.986

Genes

ACE
GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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