Article
Genetic polymorphisms of the adrenergic system and implantable cardioverter-defibrillator therapies in patients with heart failure.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 1 May 2010
Chemello Diego, Rohde Luis E, Santos Kátia G, Silvello Daiane, Goldraich Lívia, Pimentel Maurício, Rosa Priscila R, Zimerman Leandro, Clausell Nadine
Abstract excerpt
AIMS: We investigated whether the combination of beta(1)-Gly389Arg and GNB3 C825T, two genetic polymorphisms strictly related to adrenergic system modulation, could act as predictors of appropriate therapies in patients with heart failure (HF) using implantable cardioverter-defibrillators (ICDs)....
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