Article
C825T polymorphism of the G-protein beta3 subunit gene and atrial fibrillation: association of the TT genotype with a reduced risk for atrial fibrillation.
American heart journal - 1 Sept 2004
Schreieck Juergen, Dostal Stefan, von Beckerath Nicolas, Wacker Annette, Flory Michelle, Weyerbrock Sonja, Koch Werner, Schömig Albert, Schmitt Claus
Abstract excerpt
BACKGROUND: A polymorphism consisting of a C825T substitution in the G-protein beta(3) subunit gene (GNB3) has been associated with enhanced human atrial inward rectifier potassium currents regarding the TT genotype. Therefore, we investigated a possible impact of the GNB3 C825T polymorphism on atrial fibrillation in an association study. METHODS: Two hundred ninety-one consecutive patients admitted to our center...
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