Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Helicobacter hepaticus infection promotes colon tumorigenesis in the BALB/c-Rag2(-/-) Apc(Min/+) mouse.

Infection and immunity - 1 Jun 2008

Nagamine Claude M, Sohn Jane J, Rickman Barry H, Rogers Arlin B, Fox James G, Schauer David B

Abstract excerpt

Adenomatous polyposis coli (APC) mutations are linked to human and mouse colorectal cancers. The Apc multiple intestinal neoplasia (Min) mouse mutation causes adenomas to develop throughout the small and large intestines. The BALB-Min (C.B6-Apc(Min/+)) congenic strain was generated by backcrossing into BALB/c the Apc(Min) allele from C57BL/6J-Apc(Min/+) mice. BALB-Min mice have a low tumor multiplicity (27.4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli Protein
Share to Colonic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrointestinal Tract

Share to Gene Deletion

Share to Helicobacter Infections

Share to Hepatitis

Share to Longevity

Share to Mice, Inbred BALB C

Source

Open in PubMed Open full text

Identifiers

PMID: 18411292
DOI: 10.1128/IAI.01604-07
PMCID: PMC2423080

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Helicobacter hepaticus infection promotes colon tumorigenesis in the BALB/c-Rag2(-/-) Apc(Min/+) mouse.PMID 18411292Read ↗

Bacterial infection promotes colon tumorigenesis in Apc(Min/+) mice.Semantic proximity Read ↗

Intestinal immune responses in wild-type and Apcmin/+ mouse, a model for colon cancer.Semantic proximity Read ↗

Induction of inflammatory bowel disease accelerates adenoma formation in Min +/- mice.Semantic proximity Read ↗

Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation.Semantic proximity Read ↗

Analysis of reciprocal congenic lines reveals the C3H/HeJ genome to be highly resistant to ApcMin intestinal tumorigenesis.Semantic proximity Read ↗

Multistep carcinogenesis of the colon in Apc(Min/+) mouse.Semantic proximity Read ↗

Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.Semantic proximity Read ↗

Generation of a unique strain of multiple intestinal neoplasia (Apc+/Min‐FCCC) mice with significantly increased numbers of colorectal adenomasSemantic proximity Read ↗

Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APCMin/+ Mice.Semantic proximity Read ↗

Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice.Semantic proximity Read ↗

ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias.Semantic proximity Read ↗

Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.