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Article

Cardiomyocyte-mediated contact programs human mesenchymal stem cells to express cardiogenic phenotype.

The Journal of thoracic and cardiovascular surgery - 1 Jul 2003

Rangappa Sunil, Entwistle John W C, Wechsler Andrew S, Kresh J Yasha

Abstract excerpt

BACKGROUND: Intercellular crosstalk and cellular plasticity are key factors in embryogenesis and organogenesis. The microenvironment plays a critical role in directing the progression of stem cells into differentiated cells. We hypothesized that intercellular interaction between adult human mesenchymal stem cells and adult human cardiomyocytes would induce stem cells to acquire the phenotypical characteristics of...

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Identifiers

PMID: 12878947
DOI: 10.1016/s0022-5223(03)00074-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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