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Article

Multidrug resistance-associated antigens on drug-sensitive and -resistant human tumour cell lines.

British journal of cancer - 1 Jul 1991

Mirski S E, Cole S P

Abstract excerpt

In this paper the biochemical properties of the antigens detected by six murine monoclonal antibodies (MAbs) are described. These MAbs react selectively with the multidrug-resistant small cell lung cancer (SCLC) cell line, H69AR, compared to its sensitive parent cell line, H69 (Mirski & Cole, 1989). Because H69AR cells do not overexpress P-glycoprotein, the antigens detected by these MAbs may be markers for...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Antibodies, Monoclonal
Antigens, Neoplasm
Carcinoma, Small Cell
Cell Line
Drug Resistance
Electrophoresis, Gel, Two-Dimensional
Electrophoresis, Polyacrylamide Gel
Enzyme-Linked Immunosorbent Assay
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunoblotting

Lung Neoplasms

Membrane Glycoproteins

Molecular Weight

Source

Open in PubMed Open full text

Identifiers

PMID: 1677258
DOI: 10.1038/bjc.1991.232
PMCID: PMC1977290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1677258-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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