Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ApoE allelic variability influences pupil response to cholinergic challenge and cognitive impairment.

Genes, brain, and behavior - 1 Apr 2007

Scinto L F M

Abstract excerpt

Exaggerated pupil response to dilute tropicamide has been suggested as an early biological marker for Alzheimer's disease. The current study links apolipoprotein E (ApoE) allelic variability to the magnitude of pupil response in a sample of community-dwelling elderly without a diagnosis of Alzheimer's disease or dementia. Possession of an epsilon 4 allele influences both the likelihood of exhibiting an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Topical
Share to Apolipoprotein E4
Share to Attention

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognition

Share to Cognition Disorders

Share to Gene Dosage

Share to Muscarinic Antagonists

Share to Reference Values

Source

Identifiers

PMID: 16764677
DOI: 10.1111/j.1601-183X.2006.00247.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ApoE allelic variability influences pupil response to cholinergic challenge and cognitive impairment.PMID 16764677Read ↗

Apolipoprotein E epsilon 4 allele and pupillary response to tropicamide.Semantic proximity Read ↗

Pupil dilatation assay by tropicamide is modulated by apolipoprotein E epsilon 4 allele dosage in Alzheimer's disease.Semantic proximity Read ↗

Pupillary dilation responses as a midlife indicator of risk for Alzheimer’s Disease: Association with Alzheimer’s disease polygenic riskSemantic proximity Read ↗

Pupil response biomarkers distinguish amyloid precursor protein mutation carriers from non-carriers.Semantic proximity Read ↗

Pupillary dilation responses as a midlife indicator of risk for Alzheimer's disease: association with Alzheimer's disease polygenic riskSemantic proximity Read ↗

Pupillary Responses as a Biomarker of Early Risk for Alzheimer’s DiseaseSemantic proximity Read ↗

Biological markers for the clinical diagnosis of Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease.Semantic proximity Read ↗

A distinctive interaction between memory and chronic daytime somnolence in asymptomatic APOE e4 homozygotes.Semantic proximity Read ↗

Lorazepam Challenge for Individuals at Varying Genetic Risk for Alzheimer Disease.Semantic proximity Read ↗

Age and APOE-epsilon4 genotype influence the effect of physostigmine infusion on the in-vivo distribution volume of the muscarinic-2-receptor dependent tracer [18F]FP-TZTP.Semantic proximity Read ↗

Age- and genotype-related neurophysiologic reactivity to oxidative stress in healthy adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.