Article
Pupil response biomarkers distinguish amyloid precursor protein mutation carriers from non-carriers.
Current Alzheimer research - 1 Oct 2013
Frost Shaun M, Kanagasingam Yogesan, Sohrabi Hamid R, Taddei Kevin, Bateman Randall, Morris John, Benzinger Tammie, Goate Alison, Masters Colin L, Martins Ralph N
Abstract excerpt
CONTEXT: Alzheimer's disease (AD) is usually only diagnosed many years after pathology begins. Earlier detection would allow emerging interventions to have a greater chance to preserve healthy brain function. A rare form of Alzheimer's disease, caused by autosomal-dominant mutations, affects carriers with 100% certainty and at a younger age specific to their mutation. Studying families with these mutations allows...
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