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Article

Using mutual information to measure the impact of multiple genetic factors on AIDS.

Journal of acquired immune deficiency syndromes (1999) - 1 Jul 2006

Nelson George W, O'Brien Stephen J

Abstract excerpt

Since the discovery of the 32-base-pair deletion in the CCR5 chemokine receptor gene (CCR5-Delta32) and its effect on HIV-1 infection and AIDS progression, many genetic factors affecting AIDS have been identified. Here we quantify the impact of 13 of these factors on AIDS progression using a new statistic based on the mutual information between causal factors and disease, the explained fraction. The influence of...

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Identifiers

PMID: 16763524
DOI: 10.1097/01.qai.0000219786.88786.d8

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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