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Article

Causal pathways of the effects of age and the CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on AIDS development.

Journal of acquired immune deficiency syndromes (1999) - 1 Jul 2005

Geskus Ronald B, Meyer Laurence, Hubert Jean-Baptiste, Schuitemaker Hanneke, Berkhout Ben, Rouzioux Christine, Theodorou Ioannis D, Delfraissy Jean-François, Prins Maria, Coutinho Roel A

Abstract excerpt

OBJECTIVE: To investigate the causal pathways by which age and the CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles influence progression to AIDS. DESIGN: Analysis of follow-up data from 2 cohort studies among homosexual men (n=400), having >10 years of follow-up. METHODS: The effects of the 4 cofactors on the CD4 and HIV-1 RNA trajectories after seroconversion were modeled in a random-effects model. A proportional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, CCR2

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Identifiers

PMID: 15980693
DOI: 10.1097/01.qai.0000142017.25897.06

Genes

CCR2
CCR5

Provenance

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