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Article

Hepatocellular carcinoma and estrogen receptors: Polymorphisms and isoforms relations and implications.

Medical hypotheses - 1 Jan 2016

Baldissera V D, Alves A F, Almeida S, Porawski M, Giovenardi M

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common primary tumor of liver and its incidence continues to increase worldwide. HCC is a disease with multifactorial causes and genetic variability has been discussed as a risk factor for its development. Liver is a hormone-sensitive organ and therefore is influenced by gonadal hormones, such as estrogen. Estrogen is known to participate in various biological functions,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26804600
DOI: 10.1016/j.mehy.2015.11.030

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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