Article
Large scale copy number variation (CNV) at 14q12 is associated with the presence of genomic abnormalities in neoplasia.
BMC genomics - 6 Jun 2006
Braude Ilan, Vukovic Bisera, Prasad Mona, Marrano Paula, Turley Stefanie, Barber Dwayne, Zielenska Maria, Squire Jeremy A
Abstract excerpt
BACKGROUND: Advances made in the area of microarray comparative genomic hybridization (aCGH) have enabled the interrogation of the entire genome at a previously unattainable resolution. This has lead to the discovery of a novel class of alternative entities called large-scale copy number variations (CNVs). These CNVs are often found in regions of closely linked sequence homology called duplicons that are thought...
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