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DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH

3 Jun 2008

Abstract excerpt

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are rare and highly aggressive soft tissue tumors showing complex chromosomal aberrations. In order to identify recurrent chromosomal regions of gain and loss, and thereby novel gene targets of potential importance for MPNST development and/or progression, we have analyzed DNA copy number changes in seven high-grade MPNSTs using microarray-based...

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PMID: 18522746
DOI: 10.1186/1476-4598-7-48

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