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Article

Structural genome variations in individuals with childhood cancer and tumour predisposition syndromes.

European journal of cancer (Oxford, England : 1990) - 1 Jun 2013

Hopman Saskia, Merks Johannes, Eussen Hubertus, Douben Hannie, Snijder Simone, Hennekam Raoul, de Klein Annelies, Caron Huib

Abstract excerpt

BACKGROUND: Previous studies have shown a high prevalence of syndromes in children with cancer. We described four patterns of co-occurring morphological abnormalities indicating new tumour predisposition syndromes. These patterns were named after their key-abnormalities: blepharophimosis (BP), epicanthal folds (EF), asymmetric lower limbs (LLA) and Sydney creases (SC) pattern. The purpose of our study was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23473611
DOI: 10.1016/j.ejca.2013.02.002

Genes

BCL9
PCM1
TRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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