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Article

Genetic alterations in chondrosarcomas - keys to targeted therapies?

Cellular oncology (Dordrecht, Netherlands) - 1 Apr 2014

Samuel Andre M, Costa Jose, Lindskog Dieter M

Abstract excerpt

BACKGROUND: Chondrosarcomas are malignant tumors of chondrocytes and represent the second most common type of primary bone tumors. Within the context of normal chondrogenesis, this review summarizes results from recent research outlining the key molecular changes that occur during the development of this sarcoma type. RESULTS: Current data support the notion that a two-hit scenario, common to many tumors, also...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24458248
DOI: 10.1007/s13402-014-0166-8
PMCID: PMC13004474

Genes

IHH
EXT1
EXT2
IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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