Article
Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype.
Histopathology - 1 Oct 2015
Cleven Arjen H G, Zwartkruis Evita, Hogendoorn Pancras C W, Kroon Herman M, Briaire-de Bruijn Inge, Bovée Judith V M G
Abstract excerpt
AIMS: Periosteal chondrosarcoma is a rare, malignant cartilage-forming neoplasm originating from the periosteal surface of bone. We collected 38 cases from the archives of the Netherlands Committee on Bone Tumours, with the aim of studying histological features and evaluating the involvement of isocitrate dehydrogenase 1 (IDH1), EXT, Wnt/β-catenin, the pRB pathway (CDK4 and p16), and the TP53 pathway (p53 and...
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