Article
Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE.
DNA sequence : the journal of DNA sequencing and mapping - 1 Feb 2006
Caminschi Irina, Vandenabeele Stephane, Sofi Mariam, McKnight Andrew J, Ward Neil, Brodnicki Thomas C, Toy Tracey, Lahoud Mireille, Maraskovsky Eugene, Shortman Ken, Wright Mark D
Abstract excerpt
The epidermal growth factor-transmembrane seven (EGF-TM7) family are proteins that express EGF-like domains at their extracellular N-terminus coupled to a classical seven transmembrane (TM7) cassette. Recently, we identified, in mice, a novel member of this family termed FIRE (EMR-4). Here, we present the structure of the mouse and human FIRE genes. The structures of the two genes are strikingly similar, with the...
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