Article
The unique cytoplasmic domain of the human integrin variant beta4E is produced by partial retention of intronic sequences.
Biochemical and biophysical research communications - 27 Jun 1997
van Leusden M R, Kuikman I, Sonnenberg A
Abstract excerpt
A novel cytoplasmic splice variant of the human beta4 integrin subunit has been identified by reverse transcription polymerase chain reaction using mRNA from cultured keratinocytes as the template. This fifth beta4 variant, called beta4E, is expressed in a wide variety of tissues including the ep...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Antigens, CD
- Base Sequence
- Cytoplasm
- DNA, Complementary
- Exons
- Genetic Variation
- Humans
- Integrin beta4
- Integrins
- Introns
- Molecular Sequence Data
- Polymerase Chain Reaction
- RNA, Messenger
- Recombinant Proteins
- Transcription, Genetic