TM7XN1, a novel human EGF‐TM7‐like cDNA, detected with mRNA differential display using human melanoma cell lines with different metastatic potential1

Abstract excerpt

We have identified a novel 3845 bp cDNA differentially expressed in a human melanoma metastasis model. Northern blot analysis showed expression in the poorly and intermediately metastasizing cell lines and a marked downregulation in the highly metastatic cell lines. Using RT-PCR expression was also seen in several other tumor cell lines and normal cell types of human origin. cDNA sequence analysis revealed an ORF...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Adhesion Molecules Research
• Share to Monoclonal and Polyclonal Antibodies Research
• Share to RNA and protein synthesis mechanisms