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Article

Neurological abnormalities in caveolin-1 knock out mice.

Behavioural brain research - 15 Sept 2006

Trushina Eugenia, Du Charme Jordan, Parisi Joseph, McMurray Cynthia T

Abstract excerpt

Caveolin-1 is the defining structural protein in caveolar vesicles, which regulate signal transduction and cholesterol trafficking in cells. In the brain, cav-1 is highly expressed in neurons and glia, but its function in those cell types is unclear. Mice deficient in cav-1 (CavKO) have been developed to test functional roles for cav-1 in various tissues. However, neurological phenotypes associated with loss of...

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Identifiers

PMID: 16750274
DOI: 10.1016/j.bbr.2006.04.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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