Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.

doi:10.1523/JNEUROSCI.5244-10.2011

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Article

Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 Apr 2011

Banks Gareth T, Haas Matilda A, Line Samantha, Shepherd Hazel L, Alqatari Mona, Stewart Sammy, Rishal Ida, Philpott Amelia, Kalmar Bernadett, Kuta Anna, Groves Michael, Parkinson Nicholas, Acevedo-Arozena Abraham, Brandner Sebastian, Bannerman David, Greensmith Linda, Hafezparast Majid, Koltzenburg Martin, Deacon Robert, Fainzilber Mike, Fisher Elizabeth M C

Abstract excerpt

The cytoplasmic dynein complex is fundamentally important to all eukaryotic cells for transporting a variety of essential cargoes along microtubules within the cell. This complex also plays more specialized roles in neurons. The complex consists of 11 types of protein that interact with each other and with external adaptors, regulators and cargoes. Despite the importance of the cytoplasmic dynein complex, we know...

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PMID: 21471385
DOI: 10.1523/JNEUROSCI.5244-10.2011
PMCID: PMC3096546

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