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Article

Genetic variants of collagen III and abdominal aortic aneurysm.

European journal of vascular surgery - 1 Apr 1991

Powell J T, Adamson J, MacSweeney S T, Greenhalgh R M, Humphries S E, Henney A

Abstract excerpt

Collagens provide the tensile strength of the aortic wall. Variations in collagen structure are recognised in Ehlers Danlos syndrome type IV and could also be associated with a predisposition to aortic aneurysm. The frequency of some minor genetic variants of type III collagen, present in the normal population, can be detected by restriction enzyme digestion of genomic DNA from peripheral leucocytes. The...

Topics

Aged
Alleles
Aorta, Abdominal
Aortic Aneurysm
Collagen
Female
Genetic Variation
Humans
Male
Muscle, Smooth, Vascular
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tensile Strength

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Identifiers

PMID: 1674699
DOI: 10.1016/s0950-821x(05)80679-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1674699-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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