A single nucleotide polymorphism in exon 3 of the kallikrein 1 gene is associated with large but not small abdominal aortic aneurysm.

doi:10.1016/j.atherosclerosis.2011.04.017

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Article

A single nucleotide polymorphism in exon 3 of the kallikrein 1 gene is associated with large but not small abdominal aortic aneurysm.

Atherosclerosis - 1 Aug 2011

Biros Erik, Norman Paul E, Walker Philip J, Nataatmadja Maria, West Malcolm, Golledge Jonathan

Abstract excerpt

OBJECTIVE: Abdominal aortic aneurysm (AAA) is a late onset degenerative condition with an inherited component thought to be due to multiple risk alleles. A locus on chromosomes 19q13 has been previously associated with AAA. The gene encoding kallikrein 1 (KLK1) is located on chromosome 19q13 and the single nucleotide polymorphism (SNP) rs5516 has been previously shown to lead to structural changes in the KLK1...

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PMID: 21571276
DOI: 10.1016/j.atherosclerosis.2011.04.017

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KLK1

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