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Article

Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein.

Journal of molecular medicine (Berlin, Germany) - 1 Aug 2006

Waza Masahiro, Adachi Hiroaki, Katsuno Masahisa, Minamiyama Makoto, Tanaka Fumiaki, Doyu Manabu, Sobue Gen

Abstract excerpt

Abnormal accumulation of disease-causing protein is a commonly observed characteristic in chronic neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and polyglutamine (polyQ) diseases. A therapeutic approach that could selectively eliminate would be a promising remedy for neurodegenerative disorders. Spinal and bulbar muscular atrophy (SBMA), one of the polyQ diseases, is a late-onset...

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PMID: 16741751
DOI: 10.1007/s00109-006-0066-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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